Read More

27 COMMENTS

  1. >Superior to any current anti-obesity approaches

    Superior to proper diet and regular exercise? That’s a pretty bold claim for something that isn’t even close to human trials yet.

  2. Unless your girth has started bending the laws of physics around your waist, weight loss is easy.

    You take in fewer calories than you expend per day and you magically start becoming less of a grotesque flesh bubble.

  3. If this works the way I think it might work. This drug alone could save countless lives. What they did was they took the good stuff from grape skin, and then surrounded that with a nanoshell to get the stuff where it needs to be. Which then turns a long term storage type of fat into a short term storage type of fat, which is mostly used to keep you warm. So if you want to loose weight extra fast you could stand in a freezer. I’m kidding on that last part. Hypothermia is a sneaky devil.

  4. Ah, the reddit public health experts are here to make their usual prescription. If only everyone who’s actually studied the problem would realize that the solutions are always so simple.

  5. 40% reduction in subcutaneous fat and a 50% reduction in visceral fat, which is found inside the abdomen, as well as an improved insulin balance to maintain blood glucose, an improvement in lipid stability and reduced inflammation after only five weeks of treatment. … With minimal side effects

    Sounds great! Especially for people who are insulin resistant or have type two diabetes.

  6. Worth reading whole article but here’s what everyone wondering

    >Previous research on resveratrol, a nutrient commonly found in the skin of red grapes and a variety of berries, showed that it can increase brown and beige adipocyte formation – possibly transformed from adipose stromal cells (ASCs) in white fat – and therefore can have an effect in combatting obesity by enhancing fat burning. The problem, however, is that resveratrol was very difficult to deliver into the white fat it must target. Resveratrol does not dissolve well in water or body fluid and is highly subject to chemical alterations in the liver, so an oral delivery was impractical.

    >…at the University of Tennessee have invented a biocompatible and biodegradable nanoparticle that could enclose the resveratrol, increasing its abilities to dissolve. This nanoparticle system can deliver resveratrol directly into ASCs within white fat and transform them into beige adipocytes and other types of cells.

    >…In their animal study through intravenous injection, these nanoparticles targeted delivery of resveratrol to ASCs in subcutaneous white fat – the jiggly fat just under the skin – and resulted in significant browning of the white fat. That translated to a 40% reduction in subcutaneous fat and a 50% reduction in visceral fat, which is found inside the abdomen, as well as an improved insulin balance to maintain blood glucose, an improvement in lipid stability and reduced inflammation after only five weeks of treatment.

  7. Pharmacological approaches are needed

    Just diet and exercise advice isn’t working

    Food is too abundant and our entire society is built for you to not having to move

    Larger societal changes will take too long to address adult health issues today

  8. And the real take-away from this story:

    >With a patent filed on the nanoparticle delivery system, Wang is looking into future commercialization opportunities to make it more available to physicians.

    Emphasis on “commercialization.”

  9. This is great but it doesn’t answer the underlying issue. Why our energy auto balance is off in fat people?

    Thin people eat what they want without getting fat or worrying about what they are eating.

LEAVE A REPLY

Please enter your comment!
Please enter your name here